Learn more about Choline uses, effectiveness, possible side effects, CHOLINE. OTHER NAME(S). Bitartre de Choline, Chlorure de Choline, Choline. Structure, properties, spectra, suppliers and links for: choline chloride, chlorure de choline [French] [INN]. choline chloride [INN]. More CHOLINE. Choline chloride ≥99%; CAS Number: ; EC Number: ; Synonym: (2-Hydroxyethyl)trimethylammonium chloride; Linear Formula: C5H14ClNO;.

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High doses can increase the risk of adverse effects Choline also seems to play a role in the development of neural tube defects Average maternal intake of choline in the highest quartile was mg daily, compared to only mg daily in the lowest quartile Foods that supply large amounts of choline are liver, muscle meats, fish, nuts, beans, peas, eggs, wheat germ, spinach, and others. Typically, chloruge above 3.

Choline chloride – Wikipedia

Vhlorure Upper Intake Levels UL, the highest chiline of intake that is likely to pose no risk of adverse effects for choline are 1 gram daily for children years, 2 grams for children years, 3 grams for children years, and 3. Infant and child development. For example, choline can be oxidized to betaine which serves as a methyl donor to convert homocysteine to methionine, then S-adenosylmethionine Retrieved from ” https: Quaternary ammonium compounds Alcohols.

Choline chloride is mass-produced with world production estimated at tons in However, we cannot guarantee the information is error-free and disclaim any liability or responsibility for any reliance on it.

Preliminary clinical research shows that taking choline bitartrate providing choline mg orally daily for 9 months does not improve global cognitive development or hippocampal-dependent memory compared to placebo in children aged 2. Orally, choline is used for liver disease including chronic hepatitis, nonalcoholic fatty liver disease, and cirrhosis.

Taking choline orally does not improve memory in elderly people with memory loss Taking choline orally, alone or in combination with lecithin, does not reduce symptoms of Alzheimer’s disease It is bifunctional, containing both quaternary ammonium salt and an alcohol. Natural Medicines disclaims any responsibility related to medical consequences of using any medical product.


Web-based Article blog or cnoline. Rule of 5 Violations: Adequate Intake AIas established by the Food and Nutrition Board of the National Institute of Medicine, for adults is mg per day for males and lactating women; females, mg per day; pregnant females, mg per day Choline concentrates in nervous tissue Journal Publishers via MeSH.

No predicted properties have been calculated for this compound. Also, evidence from two observational studies shows that higher maternal intake of choline during pregnancy is not associated with improved cognitive performance in the chlorur at the age of 3 years or 7 years; however, mean intake of choline in both of these studies was below the recommended adequate intake of mg daily However, preliminary clinical research shows that taking choline orally does not reduce cerebellar ataxia in most patients Choline is safe in children when taken in doses below the tolerable upper intake level UL, which is 1 gram daily for children years of age; 2 grams daily for children years of age; and 3 grams daily for children years of age Preliminary clinical research suggests that taking choline orally may reduce manic symptoms and other mood symptoms in some lithium-treated patients with rapidly cycling bipolar disorder compared to baseline A legal License Agreement cholinf limitations on downloading, storing, or printing content from Natural Medicines.

Also, other preliminary research suggests that using total parenteral nutrition TPN containing choline chloride 2 grams daily for 24 weeks might improve delayed visual memory, but does not improver other measures of cognitive performance, when compared to TPN alone in patients requiring long-term TPN The effect of dietary choline intake may be greatest on those with lower folate levels Choline chloride is an organic compound and a quaternary ammonium salt, an acyl group acceptor and choline acetyltransferase substrate, also is an important additive in feed especially for chickens where it accelerates growth.

In animal models, long-term withdrawal of choline from the diet can cause hepatocarcinoma Choline is safe in adults when taken in doses below the tolerable upper intake level UL of 3. Neural tube birth defects. Other commercial choline salts are choline hydroxide and choline bitartrate.


However, it may increase plasma free choline levels in some older children with this condition Preliminary clinical research suggests that taking choline as tricholine citrate mg daily for 8 weeks is less effective than intranasal budesonide mcg twice daily for reducing symptoms of allergic rhinitis For children years the AI is mg per day; years, mg per day; years, mg per day ; for infants less than 6 months, mg per day; infants months, mg per day A cross-sectional analysis of results from observational and clinical research shows that low dietary intake of choline is associated with increased fibrosis in postmenopausal women with nonalcoholic fatty liver disease but not in children, men, or premenopausal women with this condition.

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Except for any possible exceptions written into your License Agreement, no reproduction of this monograph or any content from Natural Medicines is permitted without chline permission from the publisher. Irritates lungs, eyes, skin Alfa Aesar A However, this is controversial because choline can be synthesized by the human body This chlorufe be the reason oral choline does not seem to be effective for neurodegenerative disorders of cholinergic transmission Xi Abblis Chemicals AB Taking choline orally does not seem to be effective for delaying fatigue in endurance sports Cylorure the laboratory, choline can be prepared by methylation of dimethylethanolamine with methyl chloride.

It is an important additive in feed especially for chickens where it accelerates growth. See separate listings for Phosphatidylcholine and Lecithin. Large doses can cause diarrhea Choline is used in cell membrane phospholipids and as a methyl donor for the synthesis of many endogenous compounds. For asthma, mg three times daily has been used For details about our evidence-based approach, see our Editorial Principles and Process.